Female patient, 3 years old, accompanied by her mother. She was referred to the pediatric hospital with a case of pruriginous, papulovesicular lesions ongoing for 65 hours. The lesions first appeared in the face and trunk and later on thighs, arms and forearms, associated with non-measured fever and prostration. A year ago she was diagnosed with acute lymphoblastic leukemia (ALL) and, at the time, was on maintenance chemotherapy. On examination: patient was irritated, tearful, axillary temperature of 37,0ºC. Papulovesicular lesions in all segments cited as well as those shown in the following pictures.