Case 70


A 64 year-old female patient began to present the skin lesions shown in Figures 1 and 2 six months ago. They progressively grew, without remission. At this point, there are no other lesions. She does not report previous treatments and has a negative ANA test. Skin biopsy disclosed a non-inflammatory subepidermal blister when stained by hematoxylin and eosin and direct immunofluorescence (DIF) demonstrated IgG, IgA and C3 linear deposits at the basement membrane zone (BMZ).

Which is the most likely diagnosis, taking into consideration the images and clinical data given?

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