A 21-year-old female patient, previously healthy, sought dentistry complaining of pain in the left mandibular region. A computed tomography of the face was requested (Image 1), which revealed a bone lesion in the left mandible. A total lesion exeresis was performed, which was described as an osteoma by anatomopathological examination. She denied other complaints. Reports a family history of colon carcinoma (father, grandfather and uncle), therefore a colonoscopy evaluation with biopsy (Image 2) was recommended (anatomopathological result: colonic adenomas). A total colectomy (image 3) was then performed and confirmed the previous anatomopathological result. Eighteen months after the procedure, the patient remains asymptomatic.